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Kwang Chul Chung Selected Research

Protein Aggregates

1/2018New insight into transglutaminase 2 and link to neurodegenerative diseases.
9/2016Precise assembly and regulation of 26S proteasome and correlation between proteasome dysfunction and neurodegenerative diseases.
5/2015PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation.
1/2015The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE).

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Kwang Chul Chung Research Topics

Disease

24Parkinson Disease (Parkinson's Disease)
03/2024 - 04/2002
8Neurodegenerative Diseases (Neurodegenerative Disease)
01/2018 - 04/2002
6Alzheimer Disease (Alzheimer's Disease)
06/2020 - 04/2002
6Down Syndrome (Down's Syndrome)
10/2014 - 11/2006
6Down Syndrome Critical Region
01/2014 - 11/2008
5Neuroblastoma
06/2020 - 07/2005
4Neoplasms (Cancer)
06/2020 - 01/2006
3Mitochondrial Diseases (Mitochondrial Disease)
10/2022 - 05/2015
3Inflammation (Inflammations)
10/2014 - 06/2003
3Amyloidosis
10/2008 - 03/2004
2Breast Neoplasms (Breast Cancer)
12/2017 - 05/2012
2Dementia (Dementias)
04/2007 - 12/2006
2Parkinsonian Disorders (Parkinsonism)
11/2006 - 02/2006
1Melanoma (Melanoma, Malignant)
03/2024
1Skin Neoplasms (Skin Cancer)
03/2024
1Glioblastoma (Glioblastoma Multiforme)
12/2022
1Carcinoma (Carcinomatosis)
10/2022
1Nervous System Diseases (Neurological Disorders)
01/2019
1Neuroinflammatory Diseases
01/2019
1Prion Diseases (Transmissible Spongiform Encephalopathies)
01/2018
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2018
1Lung Neoplasms (Lung Cancer)
01/2018
1Pathologic Processes
01/2018
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2017
1Psychotic Disorders (Schizoaffective Disorder)
01/2014
1Feeding and Eating Disorders (Eating Disorder)
01/2014
1Synucleinopathies
08/2011
1Adenocarcinoma
10/2008
1Dehydration (Water Stress)
05/2008
1Astrocytoma (Pilocytic Astrocytoma)
07/2007
1Huntington Disease (Huntington's Disease)
07/2005

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
03/2024 - 03/2004
13alpha-SynucleinIBA
07/2009 - 04/2002
5CalcineurinIBA
01/2014 - 06/2008
4Phosphotransferases (Kinase)IBA
03/2024 - 09/2015
4UbiquitinIBA
11/2022 - 01/2018
4Proteasome Endopeptidase Complex (Proteasome)IBA
11/2022 - 09/2016
4Amyloid (Amyloid Fibrils)IBA
06/2020 - 03/2004
4Protein AggregatesIBA
01/2018 - 01/2015
3SynucleinsIBA
06/2020 - 08/2011
3Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2018 - 02/2006
31-dodecylpyridoxal (PLD)IBA
07/2007 - 04/2002
2Protein Kinases (Protein Kinase)IBA
03/2024 - 03/2011
2mesoxalonitrileIBA
10/2022 - 01/2020
2Etoposide (VP 16)FDA LinkGeneric
10/2022 - 01/2006
2Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2020 - 01/2006
2TensinsIBA
01/2020 - 01/2006
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2018 - 05/2015
2ATP dependent 26S protease (26S proteasome)IBA
08/2017 - 09/2016
1Melanins (Melanin)IBA
03/2024
1Mechanistic Target of Rapamycin Complex 1IBA
03/2024
1TOR Serine-Threonine KinasesIBA
12/2022
1NeurotoxinsIBA
11/2022
1Peptide Hydrolases (Proteases)FDA Link
12/2021
1InterferonsIBA
06/2020
1Death-Associated Protein KinasesIBA
06/2020
1Carbonyl Cyanide m-Chlorophenyl Hydrazone (CCCP)IBA
01/2020
1Heme Oxygenase-1IBA
01/2019
1gintoninIBA
01/2019
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2019
1Protein Glutamine gamma Glutamyltransferase 2IBA
01/2018
1Interferon Type IIBA
01/2018
1PTEN-induced putative kinaseIBA
01/2018
1Deubiquitinating EnzymesIBA
12/2017
1diazonaphthalenedisulfonic acid (NDS)IBA
09/2016
1Ubiquitinated ProteinsIBA
01/2016
1Leucine (L-Leucine)FDA Link
09/2015
1AntioxidantsIBA
10/2014
1Interleukin-8 (Interleukin 8)IBA
10/2014
1CytokinesIBA
10/2014
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2014
1Serotonin (5 Hydroxytryptamine)IBA
01/2014
1Estrogens (Estrogen)FDA Link
05/2012
1Transcription Factors (Transcription Factor)IBA
04/2012
1STAT2 Transcription FactorIBA
04/2012
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
02/2012
1Tyrosine (L-Tyrosine)FDA Link
03/2011
1nonidetIBA
03/2010
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
12/2009
1AnionsIBA
12/2008
1Phosphates (Orthophosphate)IBA
12/2008
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2008
1Adenosine Triphosphate (ATP)IBA
10/2008
1Messenger RNA (mRNA)IBA
10/2008
1Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
05/2008
1NF-kappaB-Inducing KinaseIBA
02/2008
1phospholipase D1IBA
07/2007
1Dopamine (Intropin)FDA LinkGeneric
12/2006
1Liposomes (Liposome)IBA
02/2006
1IsoenzymesIBA
01/2006
1Matrix Metalloproteinases (MMPs)IBA
07/2005
1phthalocyanineIBA
03/2004
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2003
1MucinsIBA
06/2003
1Phospholipase DIBA
04/2002

Therapy/Procedure

1Therapeutics
03/2024